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Cara proteksi amino umum

Cara proteksi amino umum

1. Cbz
Amino sing dilindhungi Benziloksikarbonil (Cbz).
Deproteksi N-benzyloxycarbonyl (Cbz)
Reagen sing umum digunakake - CbzCl

2. Alok
Allyloxycarbonyl (Alloc) gugus amino sing dilindhungi

3. Trifluoroacetyl
Grup amino sing dilindhungi trifluoroacetyl

4. Benzyl
gugus amino sing dilindhungi p-methoxybenzyl (PMB).
Gugus amino sing dilindhungi 2,4-dimethoxybenzyl
Amino sing dilindhungi Benzyl
Deproteksi klompok amino sing dilindhungi benzyl
Debenzilasi N-Bn kanthi metode kloroformat

5. Pht (phthaloyl)
Gugus amino sing dilindhungi Phthaloyl (Pht).
Deproteksi klompok amino sing dilindhungi phthaloyl

6. Benzenesulfonil
Gugus amino sing dilindhungi nitrobenzenesulfonyl
p-toluenesulfonyl (Tos) proteksi amino

7. Trt
Amino sing dilindhungi trityl
Deproteksi gugus amino sing dilindhungi tritil

8. Boc
Gugus amino sing dilindhungi Tert-butoxycarbonyl
Deproteksi N-tert-butoxycarbonyl
Oxalyl Chloride De-Boc

9. Fmoc
Gugus amino sing dilindhungi methoxycarbonyl
Reagen sing umum digunakake - Fmoc-Cl

10. SEM
amino sing dilindhungi SEM

11. Liyane
Acetamide dilindhungi klompok amino
Reaksi sintesis pirol Clauson-Kaas (reaksi iki bisa digunakake minangka cara kanggo nglindhungi gugus amino, bisa ngganti proteksi Boc ganda, lan luwih stabil)
Reagen sing umum digunakake - benzyl (chloromethyl) eter
Reagen sing umum digunakake - (chloromethyl) metil eter [MOMCl]
Proteksi karbamat


Wektu kirim: Sep-07-2023